DERMIVER
 

DERMIVER ORAL SUSPENSION:

Broad spectrum oral anthelmenthic, flukicide and sustained action and higly effective against all parasitic (nematodes) larval stages of sheep and goat.

COMPOSITION:

Each ml contains

SNO

NAME

1ml Content

Content

01

Rafloxanide    IP

30mg

3.0% w/v

02

Ivermetcin       IP

1mg

0.1% w/v

04

Aqueous Base

q.s

q.s

 

Indications: Ivermetcin

 Sheep:

- Gastrointestinal worms (adult and immature): Haemonchus contortus, Ostertagia circumcinta, Trichostrongylus spp., Cooperia spp., Nematodirus spp. (including N. battus), Strongyloides papillosus, Oesophagostomum spp. and adult Charbertia ovina.

- Inhibited larval stages and benzimidazole resistant strains of H. contortus and Ostertagia circumcinta are also controlled.

- Lungworms (adult and immature): Dictyocaulus filaria.

- Nasal bot (all larval stages): Oestrus ovis.

 

Goat- Gastrointestinal worms (adult and immature): Haemonchus contortus, Ostertagia circumcinta, Trichostrongylus colubriformis, Nematodirus spathiger, Strongyloides papillosus, Oesophagostomum columbianum and adult Charbertia ovina.

- Lungworms (adult): Dictyocaulus filaria.

 

Indications: Rafoxnide

Immature and adult Fasciola in ruminants; sheep nasal bot Chan Broad Spec is effective in the treatment and control of roundworm, lungworm and fluke infections in cattle and sheep.

 Pharmacology - Ivermectin enhances the release of gamma amino butyric acid (GABA) at presynaptic neurons. GABA acts as an inhibitory neurotransmitter and blocks the post-synaptic stimulation of the adjacent neuron in nematodes or the muscle fiber in arthropods. By stimulating the release of GABA, Ivermectin causes paralysis of the parasite and eventual death. As liver flukes and tapeworms do not use GABA as a peripheral nerve transmitter, ivermectin is ineffective against these parasites.

 Rafoxanide It belongs to salicylainilide derivative, acts through uncouple Oxidative phosphorylation inhibition thus effect on parasites is energy deplation.

With half life period of 14days, it is found to bound plasma protein, uncoupling action is lethal to liver fluke and blood sucking helminthes like Haemonchus

 

Dosage & Administration 

Sheep 1ml 4kg body weight corresponding to 7.5mg Rafoxanide per kg body weight and .2mg of Ivermectin per kg body weight

Presentation:

1Litre, 500ml, 250ml and 100ml HDPE Container


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