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| VERCET |
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VERCET ORAL SUSPENSION:
For the treatment and control of ivermectin-senstive
gastro-intestinal roundworms, lungworm and adult liver fluke of cattle.
COMPOSITION:
Each ml
contains
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SNO
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NAME
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1ml
Content
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Content
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01
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Triclobendazole
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50mg
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5.0%w/v
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02
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Ivermectin
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1mg
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0.1%w/v
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03
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Aqueous
Base
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q.s
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q.s
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INDICATIONS:
For the treatment and control of ivermectin sensitive.
Gastro-intestinal
Nematodes:
ü Adult and immature (L4): Small Brown
Stomach worm (including inhibited stages)
(Ostertagia ostertagi), Barber’s pole worm (Haemonchus placel), Stomach hair
worm (Trichostrongylus axei), Intestinal
hair worm (T.colubrifirmis), Small
intestinal worm (Cooperia spp), Nodule worm, (oesophagostomum radiatum);
and
ü
Adult
stages of cooperia oncophora, c.pimctata
Oesophagostomum venuiosum, Whip Worm (Trichuris spp)
intestinal T heardworm (Strongyloides
papillosus); and Immature stages
(L4) of thin necked intestinal Worm (Nematodirus spp)
Lung Worm: (adult and immature)Dictyocalus
viviparous
Eye Worm:
Thelazia spp (adult stages)
Liver Fluke : (adult stages) Fasciola hepatica
INDICATIONS:
Triclobendazole:
Very
effective against all stages of amphistomes and para amphistomes.
For
the treatment and control of early immature, and mature (adults) liver flukes
Fasciola gigntica Fasciola hepatica in Sheep and Goat.
Pharmacology :
Ivermectin
is an avermectin macrocyclic lactone. It interacts with glutamate-gated
chloride ion channels. By increasing membrane permeability to chloride ions it
causes irreversible neuromuscular blockade in nematodes and arthropods leading
to paralysis and death. Beside its effectiveness against ticks, mites and
insects ivermectin is a broad spectrum anthelmintic effective against mature
and immature stages of nematodes, including inhibited stages and strains
resistant to other anthelmintic classes.
Triclabendazole
is a benzimidazole. It binds to tubulin impairing intracellular transport
mechanisms and interferes with protein synthesis. Triclabendazole is
specifically effective against all 3 stages of Fasciola. The unique efficacy
against early immature and immature stages makes
VERCET particularly useful for the treatment
of outbreaks of acute and subacute fasciolosis and for the strategic control of
Fasciola infections.
Triclabendazole is active against liver
fluke, however unlike all the other benzimidazole, triclabendazole has no
activity roundworm
In cattle & sheep triclabendazole at 10
mg/kg, PO, is highly effective against immature Fasicola hepatica in the liver
parenchyma and agaist the mature stages in the bile ducts.
The maximum tolerated dose in the target
spices is 200 mg/kg thus the safety margin is 20 times the therapeutic dose.
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Dosage & Administration
Sheep: 1 ml
of VERCET
ORAL SUSPENSION per 5 kg bodyweight, corresponding to 0.2 mg Ivermectin and 10 mg triclabendazole per
kg.
PRESENTATION:
1LTR, 500ML,
250ML, 100ML HDPE Container
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